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“Simulation for Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective (Drugs and the Pharmaceutical Sciences Book 127) (English Edition)”,作者:[Hui Kimko, Stephen B. Duffull]

Simulation for Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective (Drugs and the Pharmaceutical Sciences Book 127) (English Edition) 1第一 版本, Kindle电子书

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目录

Introduction to Simulation for Design of Clinical Trials, H.C. Kimko and S.B. Duffull MODELS FOR SIMULATION Input-Output Models, N.H. G. Holford Defining Covariate Distribution Models for Clinical Trial Simulation, D.R. Mould Protocol Deviations and Execution Models, H. Kastrissios and P.l Girard Determination of Model Appropriateness, P.J. Williams and E. I. Ette COMPUTATION IN SIMULATION Computational Considerations in Clinical Trial Simulations, J.C. Pezzullo and H.C. Kimko ANALYSES OF THE SIMULATIONS Analysis of Simulated Clinical Trials, E.I. Ette, C.J. Godfrey, S. Ogenstad, and P.J. Williams Sensitivity Analysis of Pharmacokinetic and Pharmacodynamic Models in Clinical Trial Simulation and Design, I.A. Nestorov Choice of Best Design, J.P.R. Monteleone and S.B. Duffull PERSPECTIVES ON CLINICAL TRIAL SIMULATION Clinical Trial Simulation (CTS): A Regulatory Clinical Pharmacology Perspective, P.I.D. Lee and L.J. Lesko Academic Perspective: Modeling and Simulation as a Teaching Tool, N.H.G. Holford and M.O. Karlsson Modeling and Simulation of Clinical Trials: An Industry Perspective, T. Goggin, R. Gieschke, G. Pillai, B. Fotteler, P. Jordan, and J.-L. Steimer History-Informed Perspectives on the Modeling and Simulation of Therapeutic Drug Actions, J. Urquhart APPLICATIONS Evaluation of Random Sparse Sampling Designs for a Population Pharmacokinetic Study: Assessment of Power and Bias Using Simulation, M.M. Hutmacher and K.G. Kowalski Use of Modeling and Simulation to Optimize Dose-Finding Strategies, J.W. Mandema and W. Wang Model-Based Integration for Clinical Trial Simulation and Design: A Phase II Case Study for Naratriptan, I.A. Nestorov, G. Graham, S.B. Duffull, and L. Aarons Prediction of Hemodynamic Responses in Hypertensive and Elderly Subjects from Healthy Volunteer Data: The Example of Intravenous Nicardipine, P. Francheteau, H. Merdjan, M. Guerret, S. Kirkesseli, P. Sassano, and J.-L. Steimer Assessment of QTc Interval Prolongation in a Phase I Study Using Monte Carlo Simulation, P.L. Bonate Optimizing a Bayesian Dose-Adjustment Scheme for a Pediatric Trial: A Simulation Study, M.R. Gastonguay, E. Gibiansky, L. Gibiansky, and J.S. Barrett Index --此文字指其他 kindle_edition 版本。

基本信息

  • ASIN ‏ : ‎ B00UVAPDTW
  • 出版社 ‏ : ‎ CRC Press; 第 1st 版 (2002年12月12日)
  • 出版日期 ‏ : ‎ 2002年12月12日
  • 语言 ‏ : ‎ 英语
  • 文件大小 ‏ : ‎ 12387 KB
  • 标准语音朗读 ‏ : ‎ 未启用
  • X-Ray ‏ : ‎ 未启用
  • 生词提示功能 ‏ : ‎ 未启用
  • 纸书页数 ‏ : ‎ 424页
  • 用户评分:
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